Julie Mathieu

Department of Comparative medicine ,the University of Washington, USA

Artificial intelligence (AI)–driven protein design offers new avenues for understanding   and   promoting   tissue    regeneration.    Integrating AI-guided  molecular  design  with  regenerative  biology  reveals  key structure–function relationships that control repair and differentiation, providing powerful tools to refine and accelerate cell differentiation protocols.   Computationally    engineered   proteins    enable    precise modeling of disease phenotypes and the systematic exploration of

molecular   mechanisms   underlying   regenerative   outcomes.   Using   these   approaches,   we investigate  neuronal  pain  perception,  muscle  regeneration,  and  dental tissue  renewal.  Our findings demonstrate  how AI-based  protein  design  can  decode  regenerative  processes  and inform targeted therapeutic strategies across medicine and dentistry.