周巨明

Principle Investigator, earned his Ph.D. from University of Texas MD. Anderson Cancer in 1995, did his postdoctoral training at University of California at Berkeley from 1995-2002. was appointed as Tenure Track Assistant/Associate Professor at the Wistar Institute, University of Pennsylvania, from 2000-2012, and was recruited to Kunming Institute of Zoology, CAS in 2011. He is interested in higher order chromatin organization and its role in genome stability, and the regulation of large gene complexes. He is also interested in the epigenetic basis in viral host interactions and animal models of viral infection. He is known for his work on insulators and insulator protein CTCF (Genes Dev 1997,2004, Mol Cell 2005, PNAS 1998, 2007,2017) and long-range regulatory DNA elements called the Promoter Targeting sequences (Cell 1999, PNAS 2007). His recent work includes RNAPII degradation during cellular stress, and how HSV-1 ensure viral transcription by preventing host RNAPII degradation (Cell Rep 2024)